Genetic disorders occur due to alterations in the primary genetic material—deoxyribonucleic acid (DNA)—of an organism.

Picture CRISPR-Cas9, a gene editing technology, as a GPS-guided scalpel: gRNA directs the Cas9 enzyme, a protein that cuts ...

This includes the labeling of the dCas9 protein, engineering of sgRNA, and the use of dCas9 orthologs from different bacterial species. CRISPR, clustered regularly interspaced short palindromic ...

CRISPR–Cas9-based therapies are widely investigated for their clinical applications. However, there are limitations ...

Through genome editing using CRISPR/Cas9, researchers stably create euglena mutants that can produce wax esters with improved cold flow, making the esters suitable as feedstock for biofuels. News ...

Integrated screening and CRISPR reveal eleven previously unknown factors essential for early embryo development. They showed ...

Across all domains of life, immune defenses foil invading viruses by making it impossible for the viruses to replicate. Most ...

Innovative research into the gene-editing tool targets influenza’s ability to replicate—stopping it in its tracks.