Chemical changes to histones, the proteins that help to pack and organize DNA inside cells, play a key role in determining what genes will be consistently activated over the course of an animal or ...

J. Wysocka et al., "WDR5 associates with histone H3 methylated K4 and is essential for H3K4 methylation and vertebrate development," Cell, 121:859-72, 2005. (Cited in 96 papers) David Allis from ...

Histone modification is an epigenetic mechanism that enables fine-tuning of gene expression. Mutation or dysregulation of proteins associated with histone modification (called “writers,” “erasers,” ...

The accurate distribution of chromosomes in an oocyte is essential for the correct transmission of genetic information to the next generation. Now, researchers from Kyushu University have demonstrated ...