People with substance use disorder—whether addicted to alcohol, cocaine, heroin, or nicotine—share a strikingly similar ...

Addiction is one of the most intensely studied conditions in modern medicine, yet even with high‑resolution brain scans and genetic tools, scientists still cannot fully explain why some people get ...

Explore the connections between the world of neuroscience and nuances of substance use disorders with our inaugural episode of In Such a Place. We’ll speak with Dr. Anna Radke, a leading expert in the ...

A systematic review reveals adolescent cannabis use alters brain structure, elevates addiction risk, and impacts cognitive ...

Nicotine addiction remains one of the most persistent public health challenges worldwide, driven by changes in the brain that reinforce repeated use and make quitting extremely difficult. For decades, ...

North Texas researchers identify gene changes in brain reward circuits that may point to new treatments for those struggling ...

Methamphetamine addiction has a way of looping back on itself. A rush of pleasure pulls you in, cravings follow, and the brain learns that the drug is the fastest route to reward. Yet scientists still ...

Scientists at The Scripps Research Institute (TSRI) have found that deep brain stimulation (DBS) can greatly reduce the compulsion to use heroin in standard rat models of addiction. Rats that were ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

New Book Addicted to Failure Exposes Why the $42 Billion Recovery Industry Profits From Relapse and Introduces the “Five Doors” Framework for Transformation Everyone walks through these five doors.